Searchable abstracts of presentations at key conferences in endocrinology

ea0070ep425 | Thyroid | ECE2020

Upregulation of HLA class I and antiviral immune responses in graves’ disease

Weider Therese , Richardson Sarah , Morgan Noel G. , Paulsen Trond H. , Dahl-Jørgensen Knut , Hammerstad Sara S.

Background: Graves’ disease (GD) is a common autoimmune disease of unknown origin. Evidence of an association between autoimmune thyroid diseases and viral infections is, however, emerging. Human leukocyte antigen (HLA) class I presents both virally and self-derived antigens to circulating immune cells and plays a crucial role in the defense against viral infections. This study aimed to investigate the presence of enterovirus and HLA class I expression in a large GD coho...